DEVELOPMENT OF GASTRO RETENTIVE FLOATING MATRIX TABLETS OF DILTIAZEM HYDROCHLORIDE

Development of Gastro Retentive Floating Matrix Tablets of Diltiazem Hydrochloride

Cervicofacial hemangiomas treated from January 2001 to December 2009 was clinically evaluated. This retrospective clinical study consisted of 42 females and 20 males with the age ranged from 20 days to 55 years. The lesions were present with-in first month in 45 patients (72.6%). Two patterns of tumor growth were evident: focal and diffuse. There were 59 focal hemangiomas (80.8%) and 14 diffuse...

Design of Gastro Retentive Drug Delivery System of Diltiazem Hydrochloride

L. K. Omray Ravishankar College of Pharmacy, Bhopal E.mail: [email protected] Abstract Gastro retentive drug delivery system of diltiazem hydrochloride was designed and evaluated for its effectiveness for the management of mild to moderate hypertension. Gastro retentive drug delivery system were prepared using polyvinyl alcohol and sodium carboxy methyl cellulose as the polymers and sodium...

Development and Evaluation of Gastro Retentive Floating Tablets of Ayurvedic Vati Formulation

Floating tablets of Marichyadi Vati were developed with an aim to prolong its gastric residence time and increase the bioavailability of drug. Rapid gastrointestinal transit could result in incomplete drug release from the drug delivery system above the absorption zone leading to diminished efficacy of the administered dose. The tablets were prepared by wet granulation technique, using HPMC E50...

Atenolol Gastro Retentive Floating Matrix Tablets: Formulation and In-Vitro Evaluation

In vitro Release Kinetics Study of Diltiazem Hydrochloride from Wax and Kollidon SR Based Matrix Tablets

Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...